IL-12R: A Potential Drug Target and Biomarker (P5682)
IL-12R: A Potential Drug Target and Biomarker
The IL-12 receptor (IL-12R), also known as IL-12 receptor alpha chain, is a protein that is expressed in a variety of tissues throughout the body. It is a member of the IL-1 family of cytokines, which are a group of cytoplasmic proteins that play a critical role in the regulation of cellular behavior and inflammation.
IL-12R is a type of cytokine that is involved in the regulation of immune responses, cell proliferation, and cell death. It is a potent stimulator of the production of IFN-纬, which is a key mediator of the immune response. IFN-纬 is a cytokine that is involved in the regulation of cell proliferation, differentiation, and death, and is a potent trigger of the production of other cytokines.
IL-12R is also involved in the regulation of cell death, as it can induce the production of pro-apoptotic cytokines, such as Bax. Bax is a protein that is involved in the regulation of cell death, and is a potent trigger of cell death in a variety of cell types.
IL-12R is a potential drug target, as it is involved in the regulation of a wide range of cellular processes, including immune responses, cell proliferation, and cell death. It is also involved in the regulation of inflammation, and is a potent inhibitor of the production of pro-inflammatory cytokines, such as TNF-伪.
IL-12R is also a potential biomarker for a variety of diseases, including cancer, as it is often expressed in the cells of cancer cells, and is involved in the regulation of cellular processes that are important for cancer growth and progression.
In conclusion, the IL-12 receptor is a protein that is involved in the regulation of a wide range of cellular processes, including immune responses, cell proliferation, and cell death. It is a potent stimulator of the production of IFN-纬, and is also involved in the regulation of cell death. As a result, IL-12R is a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of IL-12R in cellular processes and its potential as a drug and biomarker.
Protein Name: IL-12 Receptor
More Common Targets
IL-13 receptor | IL-15 receptor | IL-17 Receptor | IL-2 receptor | IL-20 receptor | IL-22 Receptor | IL-23 receptor complex | IL-27 receptor | IL-3 receptor | IL-31 Receptor | IL-4 receptor | IL-5 receptor | IL-6 receptor | IL10 | IL10RA | IL10RB | IL10RB-DT | IL11 | IL11RA | IL12A | IL12A-AS1 | IL12B | IL12RB1 | IL12RB2 | IL13 | IL13RA1 | IL13RA2 | IL15 | IL15RA | IL16 | IL17A | IL17B | IL17C | IL17D | IL17F | IL17RA | IL17RB | IL17RC | IL17RD | IL17RE | IL17REL | IL18 | IL18BP | IL18R1 | IL18RAP | IL19 | IL1A | IL1B | IL1F10 | IL1R1 | IL1R2 | IL1RAP | IL1RAPL1 | IL1RAPL2 | IL1RL1 | IL1RL2 | IL1RN | IL2 | IL20 | IL20RA | IL20RB | IL21 | IL21-AS1 | IL21R | IL21R-AS1 | IL22 | IL22RA1 | IL22RA2 | IL23A | IL23R | IL24 | IL25 | IL26 | IL27 | IL27RA | IL2RA | IL2RB | IL2RG | IL3 | IL31 | IL31RA | IL32 | IL33 | IL34 | IL36A | IL36B | IL36G | IL36RN | IL37 | IL3RA | IL4 | IL4I1 | IL4R | IL5 | IL5RA | IL6 | IL6-AS1 | IL6R | IL6R-AS1 | IL6ST